Savage Worlds: Aliens, World of the Dead, or Destiny
Here are a couple game concepts I wouldn't mind trying out through Savage Worlds, since I still don't have much experience with the game.
Aliens
I really like this setting and would like to explore both the survival aspects of it and the mythology. Let us explore Pilot ruins and deal with perhaps a global or intergalactic break out of the xenomorphs. Lots of variants born of different species, mysteries locked behind the enigmatic Pilot technology, and tense crawls through ships, space stations, infested colonies. What starts as perhaps an isolated incident soon blossoms into a fight for galactic survival.
Destiny
We are Guardians, the last line of defense for the last city on Earth. Adventuring through the solar system, facing down hostile aliens, uncovering relics of the past, establishing outposts, all of that sounds pretty cool to me. A nice mix of action, intrigue, and exploration. Seems like SW would work pretty well for it, though I'm not married to it.
World of the Dead
I'd like to play a great zombie apocalypse game focused on survival, including building up communities, scavenging, the nightly struggles. It's not so much killing zombies as it is the aspects of surviving, exploring a post-apocalyptic cityscape, and so on that interest me.