Lucrezia is a cruel and ruthless woman, much like Cesare. She is unafraid to curse her enemies in public, or use violence and poison to benefit herself.

She is both bold and independent, daring to hold romantic relationships with various men. Also had an incestuous relationship with her own brother, Cesare, and seemed to hate it when other women got close to him. In spite of this, inwardly, she is also extremely vulnerable. She was sent to King Desmond's court in Albion due to so many ill rumours of her escapades.